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First Omicron science

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  • Opublikowany 18 gru 2021
  • Viral replication is reduced in the lung tissue, but increased in the bronchi. This could indicate increased transmissibility but reduced pathogenicity.
    Link for free download of John's two text books, 159.69.48.3/
    Campbell's Pathophysiology Notes, Amazon orders for the UK, www.amazon.co.uk/dp/B012HWC8S...
    Campbell's Physiology Notes
    www.amazon.co.uk/dp/095537972...
    First video on my series on the respiratory system, www.youtube.com/watch?v=TB2lA...
    HKUMed finds Omicron SARS-CoV-2
    can infect faster and better than Delta
    in human bronchus
    researchnews.cc/news/10606/HK...
    First information on how Omicron SARS-CoV-2 infect human respiratory tract.
    Omicron infects and multiplies 70 times faster than the Delta in human bronchus,
    which may explain why Omicron may transmit faster
    Omicron infection in the lung is significantly lower than the original SARS-CoV-2,
    which may be an indicator of lower disease severity.
    This research is currently under peer review for publication.
    Pioneered the use of ex vivo cultures of the respiratory tract,
    for investigating many emerging virus infections since 2007
    Lung tissue removed for treatment of the lung
    Dr Chan and his team successfully isolated the Omicron SARS-CoV-2,
    and used this experimental to compare infection with the original and Delta variants
    24 hours after infection
    Omicron variant replicated around 70 times higher than the Delta variant and the original SARS-CoV-2 virus.
    In contrast, the Omicron variant replicated less efficiently (more than 10 times lower) in the human lung tissue than the original SARS-CoV-2 virus,
    which may suggest lower severity of disease.
    Dr Chan
    It is important to note that the severity of disease in humans is not determined only by virus replication but also by the host immune response to the infection,
    which may lead to dysregulation of the innate immune system, i.e. “cytokine storm”
    It is also noted that, by infecting many more people,
    a very infectious virus may cause more severe disease and death even though the virus itself may be less pathogenic.
    Therefore, taken together with our recent studies showing that the Omicron variant can partially escape immunity from vaccines and past infection,
    the overall threat from Omicron variant is likely to be very significant.
    Koch's postulates
    The microorganism must be found in abundance in all organisms suffering from the disease but should not be found in healthy organisms.
    The microorganism must be isolated from a diseased organism and grown in pure culture.
    The cultured microorganism should cause disease when introduced into a healthy organism.
    The microorganism must be reisolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.

Komentarze • 8 143

  • hbloc 1981
    hbloc 1981  +613

    Informative, concise and balanced. Without politicisation or scaremongering to either push an agenda or divert attention away from unwanted scrutiny. You are a credit to your profession sir. Much gratitude and thanks

  • Dawnie P
    Dawnie P  +270

    You never cease to amaze me. You have helped a lot of 'lay people' over the last two years understand this virus and balance out the hysteria caused by the media. I take it seriously but you have helped me more than you'll know. Thank you!

  • Sim Gahir
    Sim Gahir  +241

    You hauled me through my Nurses training. You're hauling me through this pandemic... thank you Sir. The world would be in less chaos if all other doctors based their practice on such rationality. Thank you thank you thank you!

  • Lun Channel

    I’m glad that more people are choosing to watch independent and professional source of information that are more knowledgeable in the medical field compared to mainstream media.

  • Petti Labelle

    This is why I like Dr.John Campbell. He says ALL of the facts that main stream media and the government conveniently leave out. I live in Canada and people here are losing their minds hearing how there are thousands of omicron cases in hospital, but the media forgets to mention that they didn't go to hospital for omicron. They went in for something else and just so happened to test positive. BIG difference.

  • Mikephx23
    Mikephx23  +59

    It’s crazy that I have been watching you since the beginning of 2020 and now we are headed to 2022. Never thought we would be still dealing with this Pandemic. I appreciate you Dr. Campbell for your wealth of knowledge.

  • Andrew Nicholls

    20 minutes of solid information that does not induce panic! I am so glad I found this channel. Thank you Dr. Campbell.

  • moneyblackblood

    I feel the need to add my voice to the chorus of thanks for you and the content you create. It is so good to learn about this pandemic (and infectious diseases in general) from such an excellent teacher.

  • Roberta Morrison

    Thank you for another clear presentation of the whys and hows. You definitely have a gift for making what is often complicated and potentially confusing, clear and easily understandable. Which is why I share your videos explaining what scientific evidence is, and the hows and whys of its importance.

  • Wazza Ravic

    If only I had someone like you as my bio teacher . I would have taken medicine

  • Ray Pardillo

    Well explained in the simplest possible way, most informative, very impressive, highly commendable esp. for us in the medical profession. Hats off, more power, Godbless you mate. 🎩👍

  • GaryGSF

    Such an excellent presentation. For a non-medical person, everything is described to be understandable. I have learnt more about this virus in several days, than nearly 2 years of government and "expert" statements have given on the media. Thanks Dr. John.

  • Kensen Hun

    Lately I have been having health anxiety issues because of pandemic and all that media stuff that they are pouring into us everyday. But your videos are always informative and calms me down a lot. Thanks a lot :)

  • Lynne McNab

    Being more of a visual learner, I appreciate the pictures and diagrams. So thank you 😊

  • Loanword Eggcorn

    Superb explanation and teaching and information and analysis, as usual. Thanks Dr. Campbell!

  • Joey SeedS

    Since the beginning .... This is the best resource for Pandemic information on the planet. ( to be summed up and explained easily and without bias ). Thank you for all you do Doc !

  • starryeyed76

    Thank you so much for this info!! I just had this variant and this answered so many questions that I had from my personal experience and symptoms but of course there was no one to explain or elaborate. This will also help me to inform others who may be searching for info and facts to help themselves. We need this transparency and science right now!!

  • B 007
    B 007  +1

    I am not a medical student. I barely pass Biology. But thank you for your easy to understand approach to the new C19 variant.

  • Doug B
    Doug B  +420

    From the beginning of your dissertations, more than a year ago, I can't believe how much we actually know about biology and the human body. I have learned so much from you.

  • Eb theDoc

    Thanks, Dr. John. Back at Hannover Med, we worked with cell cultures (calling it the “Cytology Lab” for financial reasons). With normal cells, and urological tumor populations (Kidney, Bladder, Prostate, Testicular), testing out diagnostic and treatment modalities. So you’re running in open doors, with me. Well done, Sir. I’m still primarily worried about the exploding gene pool of Omicron for the development of new variants still completely unknown as to spread and impact!