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Vitamins D and K2

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  • Opublikowany 3 mar 2021
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    Latest on Vitamin D
    Basically, consider 400 units (10 mcg) per day
    But, NHS mid Essex
    Routine screening of vitamin D levels and prescribing of Vitamin D is not advisable.
    Both clinical symptoms and risk factors must be present before measuring Vitamin D levels (25OHD).
    As yet there is no clear evidence to prove the risks from non-symptomatic Vitamin D deficiency.
    Vitamin D levels less than 30nmol/L (12ng / ml)
    Oral capsules, 40,000 units (1,000 mcg or 1 mg) colecalciferol weekly for 7 weeks
    (400 units per day = 2,800 units per week)
    Vitamin D levels 30 - 50 nmol/L (12 - 20 ng / ml)
    Buy your own, 400 units per day
    Vitamin D levels more than 50 nmol/L (20 ng / ml)
    Buy your own, consider, 400 units per day
    Vitamin K1
    Involved in blood coagulation (1929)
    Found in plant foods like leafy greens
    Vitamin K2
    Mostly bacterial origin
    Animal-based and fermented foods
    Adult vitamin K Adequate Intakes, 90 -120 mcg
    Fermented foods
    High fat dairy from grass fed cows
    Animal organs
    Gut bacteria
    Vitamin K might play a role, osteoporosis and coronary heart disease
    Vitamin K-dependent proteins
    Vitamin K2 supplements may improve bone and heart health, while vitamin K1 has no significant benefits
    Promotes bone calcification
    Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women
    May prevent tissue calcification
    Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats
    Vitamin K2 (MK-4) reduced blood vessel calcification whereas vitamin K1 did not
    Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study
    K2 may help with dental health
    Especially with vitamin D
    Links with liver cancer
    Links with preventing advanced prostate cancer
    Dietary intake of vitamin K and risk of prostate cancer in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)
    Synergistic effect with vitamin D
    Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy
    Prevalence of hypercalcemia related to hypervitaminosis D in clinical practice
    Determine the concentrations of 25-OH-vitamin D at which the risk of hypercalcemia
    N = 25,567
    Hypervitaminosis D was defined at serum 25-OH-vitamin D more than160 nmol/L (64 ng / ml)
    382 samples were identified as the first record of hypervitaminosis D
    39 presented hypercalcemia (10.2%)
    Some had 25-OH-vitamin D levels between 161 and 375 nmol/L.
    (most subjects presented hypercalcemia at serum concentrations of 25-OH-vitamin D less than 375 nmol/L, 150 ng / ml)
    In 15 subjects, hypercalcemia could be directly attributed to vitamin D
    In no case, serum calcium achieved concentrations considered as critical values (more than13 mg/dl).
    Hypercalcemia due to vitamin D represented less than 4% of the total hypervitaminosis D detected
    Less than 0.1% of the tests performed.
    No strong evidence proves that moderate amounts of vitamin D are harmful without an adequate intake of vitamin K. However, research is ongoing, and the picture might become clearer in the near future.

Komentarze • 4 930

  • dave johnson
    dave johnson Rok temu +2

    I'm a community pharmacist and often recommend your videos for clinical information. You're what the Internet was made for. Kind regards

  • Billy Doyle

    I have to applaude this one more than others John. Bravo mate. You've reduced mortality by massive amounts if just 1% of your subscribers takes action on what they've learnt from you.

  • A'Shasa
    A'Shasa  +787

    I had my yearly checkup in June. It went as it typically does until we got to the blood work. My doctor was telling me the blood work she was ordering and she had not mentioned vitamin D. I asked her why we were not checking my vitamin D levels and she said they don't. If they checked it at some point previously (prior years) and the patient was deficient they would have been told to take it and if they took it their numbers would be better, if they didn't it would not. No need to check it. I said 'Isn't there a relationship between a person's vitamin D levels and how bad COVID-19 does you?' She said yes. So during a pandemic that has killed a number of people why wouldn't doctors as a practice check for a deficiency in their patients that could potentially save them if they get COVID-19? That does not make sense to me. This pandemic has opened my eyes about the healthcare industry.

  • andrew haire

    His lecture on the heart philology is brilliant. Having had an aortic valve replacement 35 years and tried to understand the working of the heart. He’s the only lecturer that give clarity! Clarity ! Clarity, genius!

  • Tulsi Vana
    Tulsi Vana  +135

    Thanks for mentioning autoimmune diseases. I have subclinical Hashimotos (discourages me from getting vaxxed, I feel vulnerable to extra/ unresearched disturbances of my immune system) and your vid has led me to find out more quality research on the link between Vit D and autoimmune

  • Jean Lemagnen

    Again and again I so grateful to John for sharing his clarity of thoughts and his knowledge with a wider public. I cannot imagine how at the age of 88 I would have been able to keep informed and moreover learn painlessly about drugs and the pandemic, bearing in mind my native tongue is not English as well. A great teacher you are Sir, thank you.

  • Cindy Bogart
    Cindy Bogart Rok temu +403

    This is the best information on vitamin D &K2 I have ever heard. Not even my Dr. could touch on these concepts. Thanks, Dr. John for all you do to help keep us informed. It’s extremely valuable & appreciated!💫

  • Karen Hunt-Ahmed

    I’d lived in Chicago for years, always low Vitamin D levels. Moved south, but levels didn’t rise much, though I was taking about 2000 in/day sporadically. Doc told me this was plenty. Because of these videos, I began taking D religiously. After about 3 months of this, I realized I was sleeping really well and much less depression. Doc confirmed normal range. When I went to get new supply, I realized I’d actually been taking 10,000 iu/day! That’s the dose it took, but no doc had taken me seriously. Thanks to these videos encouraging us to keep up levels!

  • Tracy Heaslip

    Going back about 20 years there was a guy in Edmonton that his 17 year old son came down with MS. The Globe and Mail in Toronto Canada covered the story. The father was a geologist I believe. He decided to study the world and discovered that anybody around the equator did not come down with MS or diabetes, he contributes it to lack of vitamin D. He put his son on 4,000 units of vitamin D a day and his Son never had another MS attack.

  • Mark Gray
    Mark Gray  +35

    Just an update, in 2009 I was living in MA - USA, my levels of D3 were nonexistent and every winter I got the flu and whooping cough, my doctor put me on D3 and I have not been sick since. I also added K and Zinc to my daily consumption. I live in a retirement community now in Florida and many folks around me did get COVID and many were hospitalized and some died, I did not get sick and I was exposed to many who did get this flu. I recommend D3, K and zinc to all my friends and some are now doing this as well.

  • barbvdvelde

    I’m so admiring of the way you explain so many complex issues in such a clear easily understood manner John. Have recommended you to many. Much gratitude to you, you’re providing such an incredible service for us all. 🙏🏼

  • Mary McMann

    I take 4000 units of vitamin D. My Dr always includes a check of my Vitamin D levels in my bloodwork because a few years ago I was deficient. Thank you for your very informative videos. I learn so much from them. I’m a 78 yo woman trying to stay as healthy as my family elders who died in their 90’s and 100’s. It’s never to late to learn!

  • Ms B
    Ms B Rok temu +620

    Hi Doctor Campbell, am pleased to inform you that I have watched your videos on pharmacology and physiology and I have passed all my written exams for my nursing course. Thanks very much sir for your teaching videos.

  • Kate Makeup Looks

    Hello John, I’m really enjoying your videos, although I’m coming to this a bit late. This is very interesting. I live in Germany and am having a TLIF spinal fusion surgery next week to correct L4/L5 spondylolisthesis. My GP here has advised me to take D3 and K2 together in order to aid the bone fusion process, which will take place over the next year after the bone graft is inserted between my L4 and L5 vertebrae. This makes a lot of sense in light of the evidence you presented (very clearly and understandably) here. Thank you very much! By the way, you need to heat the sauerkraut for a few minutes for it to taste good 😉.

  • Citizen G'Kar

    I have just rewatched this presentation. It is one of your best ever.

  • Maroo
    Maroo  +5

    Hello Dr. Campbell, first of, thank you for all the information you share in such a pleasant manner with the world. I really appreciate the way you approach this all. About the origin of how much K2 is recommended, I think I've read something a couple of years ago about it being based off how much Natto (fermented soybean) is eaten by the Japanese. Natto is said to be (one of?) the richest source of vitamin K2 found in food. Maybe you could try and look into that? And now I think about, it, perhaps there's even a possible link between the low to none cases Japan has since some time now..? Japan has a large fish consumption as well, I'm thinking vitamine d3, Omega 3. Quite a stretch perhaps and yet it could play a role.

  • adzyfelly

    New to your channel Dr. Great stuff so far. You seem to answer all the questions I would ask you (im not a dr) if I were face to face having a real conversation with you. You explain the anomalies I would pick up on with my limited knowledge. Keep it going, loving the content.

  • Leia Lee
    Leia Lee  +10

    I have now watched this video 3 times and have found it very helpful. Thank you Dr. John and with your new videos out very recently looking at Vitamin D3 and K2 I have decided to now take K2 for the first time as I know I am not getting any from my diet. I started taking Vitamin D3 in February this year at a very low dose for the very first time as my levels where only very slightly above sufficient until the sun came. In Autumn I started taking a bit more still what most people would say is still a low dose and will be increasing my levels of D3 even more although they will not be anywhere near as high as what other people are taking but still quite modest.

  • An Industrious Mom
    An Industrious Mom Rok temu +929

    I went to my GP with extreme exhaustion, anger issues, up and down in emotion, and feeling borderline depressed. I thought it was baby blues or postpartum depression, but she checked my blood for vitamin d and said my numbers were through the floor. Prescribed me 50,000 IUs/week for 3 months and it was life changing! From the first 30 mins I took the first pill I felt instantly better. No more falling asleep behind the wheel (literary, I had to pull over the road to sleep smh). My previous doctor had given me anti depressants without checking for vitamin D. I wish docs would check for Vit D before prescribing anti-depressants.

  • Philippe Sandelé
    Philippe Sandelé Rok temu +27

    Given the importance of vit D in proper bone healing, in our periodontology/implantology office (Belgium), we have been testing routinely for vit D levels prior to oral implant surgery, this for approximately the past 3-4 yrs. It is surprising to see how many people, who overall are in good health, come out with low or suboptimal vit D levels.