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Vitamin D levels advised

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  • Opublikowany 16 lis 2021
  • Read the link to the original paper,
    www.mdpi.com/2072-6643/13/10/...
    Deficiency of vit D limits the performance of systems resulting in, increased spread of diseases of civilization
    Reduced protection against infections
    Reduced effectiveness of vaccination
    Covid fatality rates correlate with,
    Elderly, dark, black people, comorbidities, winter
    Blood level of 20 ng/mL, (50 nmol/L) sufficient to stop osteomalacia
    Preferable, 40-60 ng/mL (100 to 150 nmol/L)
    Vitamin D3 receptors
    Bone
    Intestine
    Pancreas
    Prostate
    Immune system cells
    Vitamin D is a powerful epigenetic regulator
    Influencing more than 2,500 genes
    Cancer
    Diabetes mellitus
    Acute respiratory tract infections
    Viral lung infections that cause ARDS
    Chronic inflammatory diseases
    Autoimmune diseases
    Multiple sclerosis
    Immunomodulatory properties
    Regulating innate and adaptive immune systems
    D3 receptors
    Monocytes/macrophages
    T cells
    B cells
    Natural killer (NK) cells
    Dendritic cells (DCs)
    Supplements
    Without calcium supplementation, even very high vitamin D3 supplementation does not cause vascular calcification
    Vitamin D3 supplementation in the range of 4000 to 10,000 units (100 to 250 µg) needed to generate an optimal 40-60 ng/mL (100 to 150 nmol/L)
    has been shown to be completely safe when combined with approximately 200 µg vitamin K2
    www.nhs.uk/conditions/vitamin...
    However, this knowledge is still not widespread in the medical community, and obsolete warnings about the risks of vitamin D3 overdoses unfortunately are still commonly circulating.
    ARDS and cytokine release syndrome
    Vitamin D3 is able to inhibit the underlying metabolic pathways
    Vitamin D3 has a protective role against ARDS caused by SARS-CoV-2.
    A rapidly increasing number of publications are investigating the vitamin D3 status of SARS-CoV-2 patients,
    and have confirmed low vitamin D levels in cases of severe courses of infection
    and positive results of vitamin D3 treatments
    Conclusions
    we recommend raising serum 25(OH)D levels to above 50 ng/mL (100 to 150 nmol/L)
    to prevent or mitigate new outbreaks due to escape mutations or decreasing antibody activity.
    At a time when vaccination was not yet available,
    patients with sufficiently high D3 serum levels preceding the infection were highly unlikely to suffer a fatal outcome.
    This correlation should have been good news when vaccination was not available but instead was widely ignored.
    the lower threshold for healthy vitamin D levels should lie at approximately 125 nmol/L or 50 ng/mL 25(OH)D3,
    which would save most lives, reducing the impact even for patients with various comorbidities.
    This is-to our knowledge-the first study that aimed to determine an optimum D3 level to minimize COVID-19 mortality
    Implications for herd immunity
    It seems clear that a good immune defense,
    does not prove protection against physical infection
    but rather against its consequences
    This “protection” was most effective at ~55 ng/mL
    Traditionally living populations in East Africa have a mean serum 25-hydroxyvitamin D concentration of 115 nmol/l
    www.cambridge.org/core/journa...
    natural vitamin D3 levels seen among traditional hunter/gatherer lifestyles,
    in a highly infectious environment,
    were 110-125 nmol/L (45-50 ng/mL)
    WHO advice may not be correct
    30 ng/mL D3 value considered by the WHO as the threshold for sufficiency
    Future mutations of the SARS-CoV-2 virus, vaccine immune escape
    the entire population should raise their serum vitamin D level to a safe level as soon as possible.
    As long as enough vitamin K2 is provided, the suggested D3 levels are entirely safe to achieve by supplementation.
    Selenium, magnesium, zinc, and vitamins A and E should also be controlled for and supplemented where necessary to optimize the conditions for a well-functioning immune system.
    Next study
    test PCR-positive contacts of an infected person for D3 levels immediately, i.e.,
    before the onset of any symptoms,
    and then follow them for 4 weeks and relate the course of their symptomatology to the D3 level,
    the same result as shown above must be obtained

Komentarze • 0

  • LBPreviews

    Not only is Dr. John Campbell a great source of objective information, I also find his videos oddly calming in these times of constant misinformation.

  • Alice Cole
    Alice Cole  +137

    I am an advanced practice nurse in the US. I wish this man had been my lecturer in nursing school. Amazing!

  • Dr. J
    Dr. J  +322

    This was one of the very best, most exciting, and hopeful Vit. D

  • Suzette Saur

    I was tested about 5 years ago for low thyroid. When the bloodwork came back, my Vit D levels were very, very low. My doc put me on Vit D3 10,000 units/day. The next year I had a higher reading, but still low. 5 years later, I am finally getting close to a normal range. I take a medical grade--only have to take 1 tablet (it contains the K2 also) as well as a medical grade B complex. It has made a huge difference in my energy, clear-headedness. My thyroid function has improved as well.

  • Cayplus👟🍃Connects

    Very few doctors and medical practitioners have taken the extra mile to discuss, present medical research and evidence in a comprehensive manner like you do. Thank you for everything that you do; very informative, relevant, and evidence-based content in this channel.

  • CptWhiteJeans

    Dr. Campbell is an example to all Doctors out there in the absurd times. I love his breakdown on studies as well. I hope he morphs his channel is health studies, supplements, drug breakdowns when the pandemic is over. I really like his approach. Thank you!

  • Polar Bear Hero

    I’m a nutritionist and all I could think when they discussed those at risk for severe Covid was that they were the same populations at risk for vitamin D deficiency. I was shocked no one else seemed to pick up on it.

  • High Physics

    Now I feel happy that I've been taking Vit D for nearly a year, beginning in winter last year. It's a pleasure to listen to you,John. Thank you for the interesting information.

  • Vickie Crabtree

    In August 2020, my PA recommended that I begin taking Vitamin D3 and Zinc in high doses. In November 2020 I contracted Covid, but even with several risk factors, I had a mild case. You have confirmed how wise she was in putting me on these supplements. I agree with you in not understanding why the government mouthpieces don't encourage the use of supplements that boost immunity. Makes me wonder how much influence the drug companies have in the halls of government.

  • Andrew Brown

    In Louisiana, USA early in the pandemic there was a startling discovery. Everyone in that state who died of COVID was low or critically low on vitamin D. My doctor had me go from 5,000 IU to 10,000 IU when I got COVID.

  • Scott Ralph

    As an add-on:

  • 123abceng app

    This year I've learned about human health more than during my whole life. Thank you, Dr. Campbell, for sharing viable knowledge.

  • Laurie Allee

    Hi Dr. Campbell! It's critically important to differentiate between vitamin K2, which the paper is recommending, and vitamin K1, which is what governments and multivitamins usually refer to when they refer to "vitamin K." Vitamin K2 is not found in measurable amounts in green leafy vegetables like Vitamin K1. Vitamin K2 is found in fermented foods and some animal products - goose liver pate and Gouda cheese, for example - so it is much less easily derived from a healthy diet. What we don't want is to increase vitamin K1, because that is implicated in increased clotting of the blood, contraindications with prescription blood thinners and increased clotting risks. The dosage suggested by the paper you highlighted is for K2 specifically, not all-inclusive "Vitamin K" which usually means K1.

  • Mark Lawrence

    Hi Dr John, just like to say your explanations are brilliant, I believe I may have had covid 19 in early 2019, before our 1st lockdown here in NZ, later in April that year. I am 59yr old brit, active farming lifestyle, splenetic, with raised factor v blood clotting levels, and suffered an "unprovoked" PE in April, after feeling crap for months, with most of the relevant symptoms. I continued to struggle with general health until about 1 month ago when I started taking D3, B6 +Mg - Iron daily, and now feel better than i have for years, amazed what a difference cheap suppliments can make in such a short time ! 😃

  • Athe ist
    Athe ist  +25

    I absolutely love and appreciate this man so much!! Thank you, Dr. Campbell, for your advice, expertise, deep insight into the human biological process and the effects of Vitamin D on our inner workings as well as the knowledge & understanding of the options we have to decrease our chances of a severe infection! 👍🏆

  • Linda Rice

    Thank you once again John, for getting this vital information out there! I wondered if you have much information yet, about the second booster we are being offered? Particularly, do you know whether it has been tailored to the latest variant doing the rounds? As in the case of the annual 'flu vaccine. Kindest regards

  • Kathleen S. LaRoche

    I think it's key for everyone considering megadoses of vitamin D to establish a baseline with the vitamin D 25 hydroxy test. I had the test done in July of this year and my number was 34.9. I am taking the recommendations of the study to bump up to 55. So I very much appreciate your sharing this information. However, not everyone needs megadoses. At the time of being tested, I was taking 1200 IU's/day, getting some summer sun (northeast USA) but probably less than the average person, and eating fatty fish at least three times a week. At the time and still, I was eating 2 cups of raw leafy green vegetables every day, which gave me sufficient K2 according to guidelines I have seen online. The concern I want to convey is that, such as myself, not everyone will need 4 to 10,000 IU's a day to reach the 50 ng/ml threshold or 55 optimum. I'm adding 800 IU's/day to see what that will test out as.

  • Joseph Oliver

    A great presentation on Vit D. One comment I would like to add is that when you talk about Vit K in foods near the end, it should be emphasized that it is K2 (menaquinone) specifically that is being talked about as the study itself points out. Vitamin K1 is the most common source that is present primarily in plant foods like leafy green vegetables. Vitamin K2, on the other hand, is found in animal products and fermented foods. Foods high in this vitamin include meat, dairy and natto. It is also produced by the beneficial bacteria in your gut microbiome. Most people do not get sufficient K2 even from animal sources and if you are vegetarian or vegan you definitely will be deficient, so supplementation is the safest bet.

  • Ole R
    Ole R  +2

    I have Ulcerative colitis (inflammatory bowel disease) that have been active for over 10 year. From covid-19 info on PLclip I got information about vitamin D. I went to the doctor and measure vitamin D level, and I had a low level. Then I started one year ago to take vitamin D every day. After a couple of weeks I started to get better. After a couple of month the disease disappear (is inactive) .

  • Stephen Vince

    My ex wife was taking her vitamin D (3000units pd) and contracted Covid. Experienced a heavy cold type illness for about ten days. My postman on the other hand wasnt taking any vit D at all and was seriously ill for five weeks. I take my 4000 units p/d religiously now. Nice one John, good advice.